DNA and RNA are the blueprints for all cells. As a science teacher, I have been looking for a way for students to build a model of DNA that shows the base pairs (A=T, C=G) in DNA and RNA (A=U, G=G).
If you want to watch a video, please visit https://youtu.be/eVgUMtTA06c for my overview of how to demonstrate these tiles.
A MAGNETIC set is now available on https://www.printables.com/model/1054477-magnetic-dna-rna-manipulative-tiles
I also wanted a way that they could use to demonstrate RNA transcription. This set has all the parts of DNA and RNA, as well as a tRNA block and Amino Acid (AA) to help model transcription.
I found some paper versions similar to this, but I wanted something reusable and shareable with other science teachers. The labs are now for sale on my teacher pay teacher site,
https://www.teacherspayteachers.com/Product/3D-Genetics-DNA-Manipulative-Lab-1-3452084
This set has the deoxyribose sugar (D) and Phosphate group (P) for the backbone, as well as the Purines (A, G) and Pyrimidienes (T,C).
For RNA, it has the Ribose sugar (R), Uracil (U), tRNA, and Amino Acid (AA). Using the tRNA block and Amino Acid piece (AA), you can use this set to build, copy, and transcribe DNA into a protein.
While these can be kept in a plastic bag, I know that storage space is at a premium for your science closet. I've kept a class set in a school lunchbox. Each set is designed for a group of 2-3 students. There is enough for 6 base pairs.
UPDATE: The D pieces has been reshaped to prevent students from putting the T & U In the wrong location and orientation.
UPDATE: The 3 prime and 5 prime markers have been reshaped.
UPDATE: The A & T letters have been transposed to better illustrate that A is a larger molecule then T & U.
UPDATE: The U piece has be switched to keep in line with the update above.
UPDATE: Expansion sets for gene editing are now published. http://www.thingiverse.com/thing:1321230
The lesson plans and lab sheets are now for sale on https://www.teacherspayteachers.com/Product/3D-Genetics-DNA-Manipulative-Lab-1-3452084
If you want to expand upon this set, I have the Amino Acid set available http://www.thingiverse.com/thing:1282936
A partial index of available restriction enzymes is posted here, https://en.wikipedia.org/wiki/List_of_restriction_enzyme_cutting_sites
If you want any enzyme model designed, please contact via PM or [email protected] to commission a model.
| DAN_msc.stl | 80.3KB | |
| Dis_35_V2.stl | 17.9KB | |
| Dis_A_V2_6.stl | 112.3KB | |
| Dis_C_V2_6.stl | 191.5KB | |
| Dis_D_V2_12.stl | 293.2KB | |
| Dis_G_V2_6.stl | 163.8KB | |
| Dis_P_V2_12.stl | 265.3KB | |
| Dis_RNA_6.stl | 331.4KB | |
| Dis_R_V2_6.stl | 167.7KB | |
| Dis_T_V2_6.stl | 137.1KB | |
| Dis_U_V2.stl | 163.9KB |
